Monalisa Soft Lidocaine 1 x 1ml

Monalisa Soft Lidocaine is formulated with 20 mg/ml non-animal hyaluronic acid, gently cross-linked to create a pliable lattice that slips through a 30 G needle yet resists migration once placed. Both e-fillers.com and jolifill.de list the identical HA load, lidocaine content (0.3 %) and confirm residual BDDE below the 2 ppm EU limit. The gel’s elastic modulus (G′ ≈ 35 Pa) mirrors native mucosal tissue, so it flexes with every smile without forming beads. Endotoxin levels stay under 0.5 EU/ml, earning the filler a Class III CE-2265 mark; no FDA 510(k) has been filed, so U.S. use is strictly off-label. In vivo, the HA network binds up to 1 000 × its weight in water, creating an immediate dermal cushion, while lidocaine blocks voltage-gated sodium channels to cut pain scores by about 40 % versus the plain formulation. Mannitol is absent; instead, a balanced pH (7.0 ± 0.5) and low free-HA fraction keep post-injection swelling under 5 %. Rheology testing after 50 000 shear cycles shows 92 % cohesion retention, translating to lasting smoothness in high-mobility zones such as perioral skin. Clinically, Monalisa Soft falls between ultra-fluid skin boosters and stiffer mid-dermis fillers, delivering a whisper of volume where even mild puffiness would be conspicuous.

Monalisa Soft Lidocaine is designed for expression-rich micro-wrinkles—barcode smoker’s lines, crow’s-feet, radial lip lines and superficial nasojugal creases. Patients aged 25–60 who have early photo-ageing but retain ligament support achieve a polished look rather than obvious augmentation. The filler’s moderate G′ lets injectors layer 0.02 ml micro-pearls intradermally without causing surface irregularities—ideal for Fitzpatrick I–V skins prone to post-filler puffiness. A typical protocol uses fanning or cross-hatching in the superficial dermis: 0.3 ml for the upper lip, 0.2 ml per crow’s-foot cluster. Because the gel integrates so smoothly, it is also popular for first-time lip hydration: 0.4 ml along the wet–dry border restores gloss without changing profile. Compared with Juvederm Volbella (15 mg/ml) Monalisa offers a touch more structure for crisp vermilion definition; versus Stylage Lips (18.5 mg/ml + mannitol) it trades antioxidant buffering for a silkier extrusion force in the Bi-SOFT syringe’s absence. Contra-indications mirror standard HA care—active infection, autoimmune flare, pregnancy, lidocaine allergy—while its tight cross-link reduces the risk of delayed inflammatory nodules.

The Monalisa Soft Lidocaine box contains one nitrogen-filled 1 ml glass syringe capped with a Luer-Lock hub, two EO-sterilised 30 G × 13 mm needles, and two peel-off lot/expiry labels for EU-MDR traceability. A moulded PETG cradle prevents plunger creep, and the FSC-certified carton lists storage 2–25 °C plus a hologram for authenticity. The multilingual IFU details aspiration guidance, hyaluronidase protocol (5 IU/0.1 ml), and safe disposal. All components are latex-free and ISO 10993 biocompatible. Shelf life is 24 months unopened; discard any residual gel after first use to maintain sterility.

Hydration peaks within seven days as HA equilibrates with tissue water; ultrasound follow-ups quoted by centralefillers.com show 70 % volumetric retention at six months and about 45 % at nine. Fine-line blurring around the lips may need an eight-month polish in heavy smokers, whereas crow’s-feet often stay smooth to month 10 thanks to lower hyaluronidase activity laterally. Because the gel swells minimally, day-one appearance is a reliable preview of the week-four outcome—no morning-after surprises. If reversal becomes necessary, Monalisa Soft dissolves predictably with low-dose hyaluronidase thanks to its moderate BDDE density.

Q1: Will my lips feel hard?
A1: No. The low G′ matrix flexes with speech and kissing, and most patients forget it is there after a week.

Q2: Can I combine Monalisa Soft with botulinum toxin?
A2: Yes. Most clinicians inject toxin first, wait ten minutes, then place the filler to avoid product mixing.

Q3: How soon may I apply lipstick or mascara?
A3: About six hours after treatment, once needle sites seal. Avoid vigorous rubbing for 24 hours.

Monalisa fillers are manufactured by Genoss Co., Ltd., Suwon, South Korea, inside ISO 13485-certified cleanrooms powered partly by solar arrays. Since 2014 the company has specialised in cross-linked HA with tight BDDE control (< 2 ppm) verified by gas chromatography. Every lot undergoes endotoxin testing, rheology mapping and accelerated-age stability trials before CE-2265 release. Packaging now incorporates 30 % recycled PET and soy-based inks as part of Genoss’ 2030 carbon-neutral pledge. Monalisa offers Soft, Mild and Hard variants, giving clinicians a flexible, science-backed portfolio for tailored facial rejuvenation.