Skip to product information
High-strength hyaluronidase enzyme (300 IU/ml) reformulated for dissolving HA fillers. Five 3 g vials—supports efficient correction in vascular compromise or overfilling events.

Préime® Hyaluronidase 300 IU/ml 5 x 3g

€159,95
Taxes included.

Class 3 Medical Device

This product is a Class 3 medical device that requires professional verification before purchase. You will need to upload proof of your medical credentials during checkout. This product is exclusively for business-to-business (B2B) sales to qualified medical professionals and facilities. We do not deliver this product to private customers.

Hyaluronidase enzyme solution for the rapid dissolution of hyaluronic acid-based dermal fillers and for enhancing tissue permeability.
• Concentration: 300 IU/ml hyaluronidase
• Indication: filler dissolution, hematoma reduction, localized edema management
• Pack Includes: 5 × 3 g vials
• Results Duration: rapid effects within 1–2 hours

Bulk Discount Pricing

Buy more and save with our volume discounts

5+ units €9,00 Save 10%
10+ units €8,00 Save 20%
20+ units €7,00 Save 30%
50+ units €6,00 Save 40%
Add multiple items to your cart to automatically apply the discount

information

Préime® Hyaluronidase contains 300 IU/ml of recombinant hyaluronidase, an enzyme that catalyzes the hydrolysis of hyaluronic acid. The enzyme breaks down the HA within dermal fillers, allowing for faster and safer correction of overfilled or misplaced injections. This product is formulated to act quickly, with the effects typically seen within 1–2 hours after injection. Préime® Hyaluronidase is used in both aesthetic medicine for filler corrections and in emergency settings to improve tissue permeability for local anesthesia. The enzyme is highly effective and stable in its formulation, offering predictable results with minimal risk of adverse reactions. sample

Préime® Hyaluronidase is indicated for the dissolution of hyaluronic acid-based fillers that may have been over-injected, misused, or caused unwanted lumps and bumps. It is also used to reduce the volume of fillers if necessary, correct the results of filler treatments, or in the case of filler-related complications. This product can also be used to improve the absorption of local anesthetics by increasing tissue permeability. It is ideal for correcting localized edema and hematomas after injections. It is administered through direct injection into the affected area. Contraindications include known allergies to hyaluronidase and active infections in the treatment area. s

Each box contains:
* 5 × 3 g vials of Préime® Hyaluronidase solution
* Vial caps and labels for traceability
* Multilingual Instructions-for-Use leaflet detailing storage (2–8 °C), application techniques, and safety precautions

All components are latex-free and meet ISO 10993 standards for safety. The unopened shelf life is 24 months.

The effects of Préime® Hyaluronidase are typically visible within 1–2 hours after treatment. The enzyme rapidly breaks down hyaluronic acid-based filler material, allowing the body to safely metabolize the filler. The speed of the treatment makes it ideal for quick corrections, and the effects are usually permanent once the filler is dissolved. For most complications, such as lumps or over-correction, one treatment session is sufficient. In cases where a more extensive correction is needed, a second treatment can be administered.

Q1: How quickly do the effects of hyaluronidase take place?
A1: Results are typically seen within 1–2 hours after injection, with filler dissolution occurring almost immediately.

Q2: Is hyaluronidase safe?
A2: Yes, when used properly, hyaluronidase is a safe and effective treatment for filler dissolution and complications. However, it is important to follow correct dosing and application techniques.

Q3: How long do the results of hyaluronidase last?
A3: The effects of hyaluronidase are permanent in the sense that it completely breaks down the hyaluronic acid-based fillers, and no residual product remains in the tissue.

Préime® Hyaluronidase is produced by Préime Aesthetics, a company known for offering safe, innovative, and scientifically supported products in the field of aesthetic medicine. The company follows strict ISO 13485-certified manufacturing processes to ensure product quality and safety. Préime Aesthetics is committed to advancing the aesthetic industry by providing products that meet the highest standards of efficacy and reliability.

Pairs well with