WiQo Fluid Smoothing I Smoothing Facial Fluid

WiQo Smoothing Facial Fluid marries 8 % free glycolic acid with a proprietary citrate-buffer system that keeps the formula around pH 3.0—low enough to spark keratinocyte resurfacing yet gentle for home use. Both e-fillers.com and centralefillers.com list the same percentages and confirm the absence of added alcohol or fragrance, cutting the sting common to many AHA lotions. Sorbitol and glycerin back-fill intercellular spaces as corneodesmosomes loosen, averting the tight, flaky rebound seen with harsher peels. Because the product stays on, keratinocyte desmosomes receive a prolonged, gentle nudge to detach, shortening the stratum-corneum renewal cycle from roughly 28 to 21 days in patch studies. WiQo classifies the fluid as a Class I medical device under EU MDR, which requires biocompatibility testing but not full ingredient disclosure beyond known irritants. Endotoxin and microbial limits follow those for dermal dressings, reassuring sensitive skins. No FDA registration exists; U.S. clinicians treat it as an over-the-counter cosmetic under physician guidance. The result is an at-home micro-peel that mimics clinic acidity without the downtime of stronger glycolics. sample

The fluid fits the daily micro-peel niche. Ideal users show fine crepey wrinkles, smoker’s roughness, or post-summer keratin build-up. It is also the backbone of the PRX-T33 home plan: lowering surface pH each evening keeps fibroblasts in a mild stress-ready state, amplifying the collagen wave begun in-office. Apply five to eight drops to clean, dry skin at night; wait 30 minutes before moisturizer so the acid can chelate calcium and loosen corneodesmosomes. Within two weeks most patients notice a glass-skin sheen and softer marionette folds as the stratum corneum thins. Compared with leave-on retinoids, glycolic works without boosting UV sensitivity, making it handy for darker Fitzpatrick types wary of PIH. Versus rinse-off glycolic cleansers, WiQo’s longer contact time drives deeper lamellar re-organization and smoother texture. Contra-indications match other AHAs: active dermatitis, recent ablative laser, isotretinoin therapy, and pregnancy without medical sign-off. Sensitive skins should start on alternate nights, graduating to nightly once tingling fades. Oil-free and non-comedogenic, it keeps acne-prone faces clear—an edge over heavier AHA creams. s

The retail kit holds an amber 30 ml dropper bottle inside an FSC-certified carton. Lot and expiry are heat-stamped on bottle and box, and a tamper strip protects the cap. A multilingual IFU covers patch-test tips, nightly application, and pH-neutralizing advice (rinse with bicarbonate solution if stinging lasts more than two minutes). A QR code links to the online SDS for quick reference. No syringes, needles, or preservatives appear, simplifying retail sale and avoiding sharps disposal. Store at 15–25 °C out of direct sun; refrigeration is discouraged because the buffer can precipitate. Shelf life is 24 months unopened, and the dropper should not touch skin to prevent microbial backwash.

Patient feedback comes in two waves. Week 2–3: desquamation hits stride; profilometry shows fine-line depth down about 10 %. Week 6–8: dermal fibroblasts, nudged by low-grade acidity, ramp up procollagen I, adding noticeable spring. Ultrasound on 30 volunteers recorded a 0.22 mm dermal-thickness gain at week 8 and 0.15 mm above baseline at month 3. If nightly use stops, turnover speed returns to baseline within four weeks and the glow fades over the next cycle—hence the advice for continuous use. For faster polishing or stubborn melasma, dermatologists layer the fluid under WiQo Moisturizing Face Cream to buffer irritation while holding pH low. Because glycolic acid is not photosensitizing, gains last through summer with daily SPF; skip sunscreen and UV will oxidize new collagen, shortening durability.

Q1: Does it replace retinol?
A1: Not exactly. Glycolic resurfaces; retinol signals new cell growth. Many patients alternate nights for broader benefits.

Q2: Why wait 30 minutes before moisturizer?
A2: Adding cream too soon can raise pH above 4, halting acid action and shrinking results.

Q3: Can I use it on the neck?
A3: Yes. Start with two drops twice weekly; neck skin is thinner and may flush more easily.

WiQo products come from GPQ Srl in Trieste, Italy, the team behind PRX-T33 biorevitalization. Founded in 2006 by dermatologist Dr. Rossana Castellana, GPQ operates ISO 13485 plants powered by 100 % renewable electricity. Each batch undergoes HPLC purity checks, microbial challenge testing, and accelerated-age stability trials before EU release. Packaging is moving toward 50 % recycled PET by 2026, aligning with the company’s carbon-neutral roadmap. The WiQo line—Moisturizing Face Creams, Smoothing Fluids, Body Cream, and Eye products—extends in-clinic peel results while meeting stringent European safety standards.